HA is produced in highest level during embryonic period of life, gradually decreases after birth. HA content is different among the crowd of the same age. For example, HA content of the premature senility patient is obviously reduced.Topical usage of HA can play the action of water retention and lubrication on the surface of the skin. Its limit is obvious. However, oral HA can increase endogenetic HA by digesting and absorbing and make skin moist, bright, springy.HA also plays important role of water retention and lubrication in other tissues and organs, such as joint cavity, blood vessel, heart and brain. Decrease of HA will lead to arthritis, arteriosclerosis, pulse disorder and brain atrophy. Oral HA can restore the normal content of HA, delay apolexis and make the body energic.At present, HA is widely applied in health and beauty food in America and Japan. It is great welcomed by the consumers.